AC Immune Receives First Milestone Payment from Lilly in Small Molecule Tau Morphomer™ Program
Lilly to pay
Recognizes progress in ACI-3024 Small Molecule Tau Morphomer™ development
“The start of the ACI-3024 Phase 1 study, represents an important advancement in the broader effort we are making and further expands our robust clinical pipeline to address neurodegenerative diseases, in particular for therapeutics and diagnostics targeting Tau.”
In the complex treatment paradigm for AD, Tau pathology is a potential therapeutic target. Tau spreads with a characteristic spatiotemporal pattern throughout the brain that coincides with both clinical symptoms and disease progression in AD. Slowing the propagation of Tau pathology may slow disease progression and reduce cognitive decline. Anti-Tau therapies already have shown promise in slowing the progression of Tau pathology in animal models.
ACI-3024 is the lead molecule being developed in the license and collaboration agreement between
The Phase 1 trial initiated in July is a randomized, placebo controlled, double blind, sequential single and multiple ascending dose study that aims to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of ACI-3024 in healthy volunteers.
Under the terms of the agreement, Lilly received worldwide commercialization rights for Tau aggregation inhibitors, including in the area of Alzheimer's disease.
For further information, please contact:
Joshua Drumm, Ph.D.
AC Immune Investor Relations
Phone: +1 646 876 5538
Phone: +1 617 792 3937
AC Immune Global Communication Lead
Phone: +44 7932 053829
|European Investors & Media
Phone: +41 79 367 6254
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Source: AC Immune SA