000100 - Document - Document and Entity Information link:presentationLink link:calculationLink link:definitionLink 010000 - Statement - Balance Sheets link:presentationLink link:calculationLink link:definitionLink 020000 - Statement - Statements of Income/(Loss) link:presentationLink link:calculationLink link:definitionLink 030000 - Statement - Statements of Comprehensive Income/(Loss) link:presentationLink link:calculationLink link:definitionLink 040000 - Statement - Statements of Changes in Equity link:presentationLink link:calculationLink link:definitionLink 050000 - Statement - Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 050100 - Statement - Statements of Cash Flows (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 060100 - Disclosure - General information link:presentationLink link:calculationLink link:definitionLink 060200 - Disclosure - Basis of preparation link:presentationLink link:calculationLink link:definitionLink 060300 - Disclosure - Summary of significant accounting policies link:presentationLink link:calculationLink link:definitionLink 060400 - Disclosure - Property, plant and equipment link:presentationLink link:calculationLink link:definitionLink 060500 - Disclosure - Right-of-use assets and lease liabilities link:presentationLink link:calculationLink link:definitionLink 060600 - Disclosure - Cash and cash equivalents and financial assets link:presentationLink link:calculationLink link:definitionLink 060700 - Disclosure - Prepaid expenses and accrued income link:presentationLink link:calculationLink link:definitionLink 060800 - Disclosure - Other current receivables link:presentationLink link:calculationLink link:definitionLink 060900 - Disclosure - Share capital link:presentationLink link:calculationLink link:definitionLink 061000 - Disclosure - Trade payables and accrued liabilities link:presentationLink link:calculationLink link:definitionLink 061100 - Disclosure - Financing obligation link:presentationLink link:calculationLink link:definitionLink 061200 - Disclosure - Revenues link:presentationLink link:calculationLink link:definitionLink 061300 - Disclosure - Expenses by category link:presentationLink link:calculationLink link:definitionLink 061400 - Disclosure - Related-party transactions link:presentationLink link:calculationLink link:definitionLink 061500 - Disclosure - Income taxes link:presentationLink link:calculationLink link:definitionLink 061600 - Disclosure - Retirement benefit plan link:presentationLink link:calculationLink link:definitionLink 061700 - Disclosure - Share-based compensation link:presentationLink link:calculationLink link:definitionLink 061800 - Disclosure - Commitments and contingencies link:presentationLink link:calculationLink link:definitionLink 061900 - Disclosure - Earnings per share link:presentationLink link:calculationLink link:definitionLink 062000 - Disclosure - Financial instruments and risk management link:presentationLink link:calculationLink link:definitionLink 062100 - Disclosure - Capital risk management link:presentationLink link:calculationLink link:definitionLink 062200 - Disclosure - Subsequent events link:presentationLink link:calculationLink link:definitionLink 070300 - Disclosure - Summary of significant accounting policies (Policies) link:presentationLink link:calculationLink link:definitionLink 080300 - Disclosure - Summary of significant accounting policies (Tables) link:presentationLink link:calculationLink link:definitionLink 080400 - Disclosure - Property, plant and equipment (Tables) link:presentationLink link:calculationLink link:definitionLink 080500 - Disclosure - Right-of-use assets and lease liabilities (Tables) link:presentationLink link:calculationLink link:definitionLink 080600 - Disclosure - Cash and cash equivalents and financial assets (Tables) link:presentationLink link:calculationLink link:definitionLink 080700 - Disclosure - Prepaid expenses and accrued income (Tables) link:presentationLink link:calculationLink link:definitionLink 080800 - Disclosure - Other current receivables (Tables) link:presentationLink link:calculationLink link:definitionLink 080900 - Disclosure - Share capital (Tables) link:presentationLink link:calculationLink link:definitionLink 081000 - Disclosure - Trade payables and accrued liabilities (Tables) link:presentationLink link:calculationLink link:definitionLink 081200 - Disclosure - Revenues (Tables) link:presentationLink link:calculationLink link:definitionLink 081300 - Disclosure - Expenses by category (Tables) link:presentationLink link:calculationLink link:definitionLink 081400 - Disclosure - Related-party transactions (Tables) link:presentationLink link:calculationLink link:definitionLink 081500 - Disclosure - Income taxes (Tables) link:presentationLink link:calculationLink link:definitionLink 081600 - Disclosure - Retirement benefit plan (Tables) link:presentationLink link:calculationLink link:definitionLink 081700 - Disclosure - Share-based compensation (Tables) link:presentationLink link:calculationLink link:definitionLink 081800 - Disclosure - Commitments and contingencies (Tables) link:presentationLink link:calculationLink link:definitionLink 081900 - Disclosure - Earnings per share (Tables) link:presentationLink link:calculationLink link:definitionLink 082000 - Disclosure - Financial instruments and risk management (Tables) link:presentationLink link:calculationLink link:definitionLink 090100 - Disclosure - General information (Details) link:presentationLink link:calculationLink link:definitionLink 090200 - Disclosure - Basis of preparation (Details) link:presentationLink link:calculationLink link:definitionLink 090300 - Disclosure - Summary of significant accounting policies (Details) link:presentationLink link:calculationLink link:definitionLink 090302 - Disclosure - Summary of significant accounting policies, Accounting Pronouncements Recently Adopted (Details) link:presentationLink link:calculationLink link:definitionLink 090400 - Disclosure - Property, plant and equipment (Details) link:presentationLink link:calculationLink link:definitionLink 090500 - Disclosure - Right-of-use assets and lease liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 090600 - Disclosure - Cash and cash equivalents and financial assets, Cash and cash equivalents and short-term financial assets (Details) link:presentationLink link:calculationLink link:definitionLink 090602 - Disclosure - Cash and cash equivalents and financial assets, Cash and cash equivalents (Details) link:presentationLink link:calculationLink link:definitionLink 090700 - Disclosure - Prepaid expenses and accrued income (Details) link:presentationLink link:calculationLink link:definitionLink 090800 - Disclosure - Other current receivables (Details) link:presentationLink link:calculationLink link:definitionLink 090900 - Disclosure - Share capital (Details) link:presentationLink link:calculationLink link:definitionLink 090904 - Disclosure - Share capital, Convertible Note Agreement an Follow-On Offerings (Details) link:presentationLink link:calculationLink link:definitionLink 090906 - Disclosure - Share capital, Shelf Registration Statement (Details) link:presentationLink link:calculationLink link:definitionLink 091000 - Disclosure - Trade payables and accrued liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 091100 - Disclosure - Financing obligation (Details) link:presentationLink link:calculationLink link:definitionLink 091200 - Disclosure - Revenues, Changes in Contract Assets and Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 091202 - Disclosure - Revenues, Recognized Revenues (Details) link:presentationLink link:calculationLink link:definitionLink 091204 - Disclosure - Revenues, Contract Revenue Attributable to Licensing Arrangements (Details) link:presentationLink link:calculationLink link:definitionLink 091206 - Disclosure - Revenues, Tau Morphomer Small Molecule - 2018 license agreement with Eli Lilly and Company (Details) link:presentationLink link:calculationLink link:definitionLink 091208 - Disclosure - Revenues, Anti-Abeta Antibody in AD - 2006 Agreement with Genentech (Details) link:presentationLink link:calculationLink link:definitionLink 091210 - Disclosure - Revenues, Anti-Tau Antibody in AD - 2012 Agreement with Genentech (Details) link:presentationLink link:calculationLink link:definitionLink 091212 - Disclosure - Revenues, Tau Vaccine in AD - 2014 Agreement with Janssen Pharmaceuticals (Details) link:presentationLink link:calculationLink link:definitionLink 091214 - Disclosure - Revenues, Tau-PET imaging agent in AD -2014 Agreement with Life Molecular Imaging (formerly Piramal Imaging SA) (Details) link:presentationLink link:calculationLink link:definitionLink 091216 - Disclosure - Revenues, Alpha-synuclein and TDP-43 PET Tracers in AD - 2016 Agreement with Biogen (Details) link:presentationLink link:calculationLink link:definitionLink 091218 - Disclosure - Revenues, Recombinant Protein Therapeutic Candidate -2017 Agreement with Essex Bio-Technology Limited (Details) link:presentationLink link:calculationLink link:definitionLink 091220 - Disclosure - Revenues, 2015 Grant from the Michael J. Fox Foundation (Details) link:presentationLink link:calculationLink link:definitionLink 091300 - Disclosure - Expenses by category (Details) link:presentationLink link:calculationLink link:definitionLink 091400 - Disclosure - Related-party transactions (Details) link:presentationLink link:calculationLink link:definitionLink 091500 - Disclosure - Income taxes (Details) link:presentationLink link:calculationLink link:definitionLink 091502 - Disclosure - Income taxes, Unrecognized Deductible Temporary Differences, Unused Tax Losses and Unused Tax Credits (Details) link:presentationLink link:calculationLink link:definitionLink 091600 - Disclosure - Retirement benefit plan (Details) link:presentationLink link:calculationLink link:definitionLink 091602 - Disclosure - Retirement benefit plan, Changes in Defined Benefit Obligation (Details) link:presentationLink link:calculationLink link:definitionLink 091604 - Disclosure - Retirement benefit plan, Changes in Fair Value of Plan Assets (Details) link:presentationLink link:calculationLink link:definitionLink 091606 - Disclosure - Retirement benefit plan, Change in Net Defined Benefit Liability (Details) link:presentationLink link:calculationLink link:definitionLink 091608 - Disclosure - Retirement benefit plan, Change in Other Comprehensive Loss (Details) link:presentationLink link:calculationLink link:definitionLink 091610 - Disclosure - Retirement benefit plan, Actuarial Assumptions and Sensitivity Analysis (Details) link:presentationLink link:calculationLink link:definitionLink 091700 - Disclosure - Share-based compensation, Plans Outstanding (Details) link:presentationLink link:calculationLink link:definitionLink 091702 - Disclosure - Share-based compensation, Weighted Average Exercise Prices (Details) link:presentationLink link:calculationLink link:definitionLink 091704 - Disclosure - Share-based compensation, Outstanding Options, Range of Exercise prices and Expiration Dates (Details) link:presentationLink link:calculationLink link:definitionLink 091706 - Disclosure - Share-based compensation, Weighted Average Grant date Fair Value and Assumptions (Details) link:presentationLink link:calculationLink link:definitionLink 091708 - Disclosure - Share-based compensation, Non-vested Share Awards (Details) link:presentationLink link:calculationLink link:definitionLink 091800 - Disclosure - Commitments and contingencies (Details) link:presentationLink link:calculationLink link:definitionLink 091900 - Disclosure - Earnings per share (Details) link:presentationLink link:calculationLink link:definitionLink 092000 - Disclosure - Financial instruments and risk management (Details) link:presentationLink link:calculationLink link:definitionLink 092200 - Disclosure - Subsequent events (Details) link:presentationLink link:calculationLink link:definitionLink