November 3, 2020

AC Immune SA
Registration Statement on Form F-3
Filed on October 23, 2020
Registration No. 333-249655 


Securities and Exchange Commission
Division of Corporation Finance
100 F Street, N.E.
Washington, D.C. 20549


Ladies and Gentlemen:


In accordance with Rule 461 under the Securities Act of 1933, as amended, the undersigned registrant hereby requests that the effective date for the Registration Statement referred to above be accelerated so that it will be declared effective at 4:00 p.m. Eastern Daylight Time on November 5, 2020 or as soon thereafter as is practicable.





AC Immune SA
By: /s/Andrea Pfeifer
  Name: Andrea Pfeifer
  Title: Chief Executive Officer
By: /s/Joerg Hornstein
  Name: Joerg Hornstein
  Title: Chief Financial Officer