|November 3, 2020|
AC Immune SA
Securities and Exchange Commission
Division of Corporation Finance
100 F Street, N.E.
Washington, D.C. 20549
Ladies and Gentlemen:
In accordance with Rule 461 under the Securities Act of 1933, as amended, the undersigned registrant hereby requests that the effective date for the Registration Statement referred to above be accelerated so that it will be declared effective at 4:00 p.m. Eastern Daylight Time on November 5, 2020 or as soon thereafter as is practicable.
|AC Immune SA|
|Name: Andrea Pfeifer|
|Title: Chief Executive Officer|
|Name: Joerg Hornstein|
|Title: Chief Financial Officer|